DNA分析GenomeComp 1.3

GenomeComp is a DNA sequence comparison tool and graphical user interface (GUI) viewer implemented in Perl/Tk. It can read one, two or three input sequences in either of FASTA, GENBANK or EMBL format, then it runs the external program BLASTN or MegaBlast to do the comparison between paired sequences in background. If the results already exist, it can skip that step and read the output file directly. Then the dynamic display of the results will show in the canvas of the main window.

GenomeComp can easily manage genome wide sequences (about several mega base pairs), so as to locate the rearrangements, insertions or deletions of genome segments between species or strains. In addition, it can show other features like repeat sequence distribution in one whole-genome sequence by self-comprison.

中科院生物物理所生物信息实验室推出的可视化的微生物基因组比较工具。它可以接受FASTA、GenBank或EMBL等多种输入数据格式，自动在后台调用BLAST包中的核酸序列比较软件进行比较操作，然后对结果进行分析和处理，过滤掉冗余的信息，最终将结果以动态的图形化方式显示出来。此软件特别适用于比较具有较近亲缘关系的物种或同一物种的不同株的基因组，可以很容易的发现出它们之间在基因组水平的变异，如插入、缺失或转置等等。源代码，130K。使用手册(英文版)，400K。