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份 库存999份
| 货号： | CDB-H5227 |
| 供应商： | ACROBiosystems |
| 英文名： | Human Fc gamma RIIIB / CD16b (NA1) Protein, His tag |
| 保存条件： | -20 |
| 规格： | 100ug/1mg |
Less than 1.0 EU per μg by the LAL method.
纯度:
>95% as determined by SDS-PAGE.
活性:
产品背景:
CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.
CD16B is also kown as FCGR3B and FCG3B, is expressed specifically by polymorphonuclear leukocytes (neutrophils) and stimulated eosinophils. CD16B is the low affinity receptor for the Fc region of immunoglobulins gamma. FCGR3B binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, FCG3B is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. CD16B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
产品描述:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.8 kDa. The protein migrates as 35-45 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
SDS-PAGE
因为难以在供应系统上进行数据同步，所以了解更多产品规格及产品数据，请移步：
http://www.acrobiosystems.cn/P1095-Human_Fc_gamma_RIIIB_%7C_CD16b_Protein_NA1_His_tag.html
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