Human LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag

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单价: 3500.00
品牌: ACROBiosystems
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更新: 2021-04-17
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货号: LA3-H52Aa
供应商: ACROBiosystems
英文名: Human LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag
规格: 100ug/1mg
内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>95% as determined by SDS-PAGE.

活性:
Immobilized Anti-LAG3 MAb, Human IgG1 at 0.5 μg/mL (100 μL/well) can bind Human LAG-3, mouse IgG2a Fc tag (Catalog # LA3-H52Aa) with a linear range of 0.8-3 ng/mL (QC tested).

产品背景:
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

产品描述:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.3 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

SDS-PAGE


 

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