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份 库存999份
| 货号： | K147-100 |
| 保存条件： | -20度 |
| 供应商： | 北京博迈斯 |
| 英文名： | Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric) |
| 规格： | 100 assays |
Assay Kit Name:
Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric)
Kit Summary:
• Detection method - Fluorescence (Ex/Em = 400/505 nm)
• Applications - Screen/study/characterize potential inhibitors of Cathepsin B.
Features & Benefits:
• Simple & convenient
• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin B
• Cathepsin B inhibitor, F-F-FMK is included in the kit
Kit Components:
• CTSB Reaction Buffer
• CTSB Reagent
• Cathepsin B (human)
• CTSB Substrate, Ac-RR-AFC (10 mM)
• CTSB Inhibitor (F-F-FMK, 1 mM)
Description:
Cathepsin B (CTSB, EC 3.4.22.1) is a lysosomal cysteine proteinase that is suggested to participate in intracellular degradation and turnover of proteins. It has also been implicated in tumor invasion and metastasis. Biovision’s Cathepsin B Inhibitor Screening Kit utilizes the ability of Cathepsin B to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin B-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin B.
Storage Conditions:
-20°C
Shipping Conditions:
gel pack
USAGE: For Research Use Only! Not For Use in Humans.
[VIP第1年] 指数:2
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