WNT Signaling Pathway PCR Array WNT信号通路基因表达PCR芯片_其它_生物芯片_仪器设备库_商城

WNT信号通路基因表达PCR芯片可用于研究与WNT介导的信号转导相关的84个基因的表达，同时测定实验组样本中经典的WNT/β-catenin信号通路活性是被激活，抑制还是没有变化。该芯片同时包含了16个通过实验验证得到的显著标志基因，通过分级运算程序可计算得到活性分值。每块芯片上都设定了一组对照通过ΔΔCT方法分别对反转效率，基因组DNA含量和PCR效率进行评估。使用该芯片研究者即能够利用该芯片简单可靠地测定经典WNT/β-catenin信号通路活性并同时检测WNT介导的信号转导相关基因的表达。
WNT Signaling Pathways: Canonical: APC, AXIN1, AXIN2, CSNK1A1, CTBP1, CTNNB1, CTNNBIP1 (ICAT), DKK1, DKK3, DVL1, DVL2, EP300, F1, FZD1, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9, GSK3B, LEF1, LRP5, LRP6, NKD1, PORCN, RUVBL1, SFRP1, SFRP4, SKP2, SOX17, TCF7, TCF7L1, WIF1, WNT1, WNT10A, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT6, WNT7A, WNT7B, WNT8A.
Planar Cell Polarity (PCP): DAAM1, DVL1, DVL2, MAPK8 (JNK1), NKD1, PRICKLE1, RHOA, VANGL2, WNT9A.
WNT/Ca+2: FZD2, NFATC1, WNT1, WNT10A, WNT11, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT9A.
WNT Signaling Negative Regulation: APC, AXIN1, AXIN2, BTRC (bTrCP), CCND1, CTBP1, CTNNBIP1 (ICAT), DKK1, DKK3, FBXW11, FRZB (FRP-3), KREMEN1, LRP6, NLK, NKD1, SFRP1, SFRP4, SOX17, WIF1.
WNT Signaling Target Genes: AXIN2, BTRC (bTrCP), CCND1, CCND2, DAB2, FOSL1 (FRA-1), JUN, MMP7, MYC, PITX2, PPARD, WISP1.
Developmental Processes: Cell Fate: CTNNB1,
DKK1, WNT1, WNT3, WNT3A.
Tissue Polarity: AXIN2, FZD2, FZD3, FZD5, FZD6, VANGL2.
Cell Growth & Prolifeion: APC, CCND1, CCND2, CTBP1, CTNNB1, CTNNBIP1 (ICAT), DAB2, EP300, FGF4, FOSL1, FZD3, JUN, LRP5, MMP7, MYC, PPARD, WISP1, WNT3A.
Cell Migion: APC, DKK1, LRP5, LRP6, RHOA, WNT1.
Cell Cycle: APC, BTRC (bTrCP), CCND1, CCND2, CTNNB1, EP300, FOSL1, JUN, MYC, RHOA, RUVBL1, TCF7L1.
Cellular Homeostasis: APC, FZD2, JUN, MYC.
Pathway Activity Signature Genes: BOD1, CALM1, CCND1, CCND2, CHSY1, CXADR, CYP4V2, HSPA12A, LEF1, MT1A, MTFP1, MTSS1, MYC, NAV2, PRMT6, SKP2.

全部商品分类

WNT Signaling Pathway PCR Array WNT信号通路基因表达PCR芯片

公司简介