Catalog Number:
100-18C
Synonyms:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
Description:
FGF-basic是23个已知的FGF家族成员之一，该家族的蛋白通过促进细胞增殖和分化而在多种组织的出生前和出生后发育，以及再生中发挥重要作用。FGF-basic为非糖基化的肝素结合生长因子，表达于脑、垂体、肾、视网膜、骨，睾丸、肾上腺、肝、单核细胞、上皮细胞和内皮细胞。FGF-basic通过FGFR 1b，1c，2c，3c和4进行信号传递。重组人FGF-basic(146 a.a.)是分子量为16.4 kDa的蛋白，由146个氨基酸残基组成。
AA Sequence:
PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Research Interests:
 | Angiogenesis/ Cardiovascular | | Cancer |
| Cell Culture | | FGF Superfamily |
| Inflammation | | Neurobiology |
| Proliferation | | Stem Cells & Differentiation |
| Wound Healing | |
Country of Origin:
USA
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[VIP第1年] 指数:1
