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Active EGF全长蛋白质
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更新： 2021-04-12
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多肽定制，抗体制备，蛋白表达，支原体检测试剂盒
多肽定制，抗体制备，蛋白表达，支原体检测
人源氧化高密度脂蛋白
人源氧化高密度脂蛋白
Human Low Density Lipoprotein (Human LDL) 人源低密度脂蛋白
Human Low Density Lipoprotein (Human LDL
Human High Density Lipoprotein（Human HDL） 人源高密度脂蛋白
Human High Density Lipoprotein（Human HD
 
 

 

  • 性质Recombinant
  • 来源E. coli

技术指标

Our Abpromise guarantee covers the use of ab9863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 形式Lyophilised
  • 补充说明Murine EGF is fully biologically active when compared with standards. The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg.
  • 浓度由溶解方法决定 

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product has been formulized from 10mM Sodium phosphate. pH 8.0.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶ADD 500UL WATER

常规信息

  • 别名
    • Beta urogastrone
    • EGF
    • EGF_HUMAN
    see all
  • 功能EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
  • 组织特异性Expressed in kidney, salivary gland, cerebrum and prostate.
  • 疾病相关Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.
  • 序列相似性Contains 9 EGF-like domains. Contains 9 LDL-receptor class B repeats.
  • 细胞定位Membrane.