Anti-HNF6抗体

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单价: 1380.00
品牌: Ybscience
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更新: 2021-05-19
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 Anti-HNF6抗体

产品编号 YB-18062R
英文名称 HNF6
中文名称 肝细胞核因子6抗体
别    名 hepatocyte nuclear factor 6 alpha; Hepatocyte nuclear factor 6; HNF 6; HNF-6; HNF6_HUMAN; HNF6A; One cut domain family member 1; One cut homeobox 1; Onecut1.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  免疫学  信号转导  转录调节因子  新陈代谢  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HNF6:351-465/465 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] Function: Transcriptional activator. Binds the consensus sequence 5-DHWATTGAYTWWD-3 on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in liver; lower expression in testis and skin. Similarity: Belongs to the CUT homeobox family. Contains 1 CUT DNA-binding domain. Contains 1 homeobox DNA-binding domain. SWISS: Q9UBC0 Gene ID: 3175 Database links:

Entrez Gene: 3175 Human

Entrez Gene: 15379 Mouse

Entrez Gene: 25231 Rat

Omim: 604164 Human

SwissProt: Q9UBC0 Human

SwissProt: O08755 Mouse

SwissProt: P70512 Rat

Unigene: 658573 Human

Unigene: 303355 Mouse

Unigene: 48812 Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Sample:  HepG2 Cell (Human) Lysate at 40 ug Hcclm3 Cell (Human) Lysate at 40 ug Liver (Mouse) Lysate at 40 ug BRL-3A Cell (Rat) Lysate at 40 ug Primary: Anti- HNF6 (bs-18062R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD