Anti-phospho-ZCWCC1 (Ser739)抗体

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单价: 1580.00
品牌: Ybscience
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更新: 2020-10-17
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 Anti-phospho-ZCWCC1 (Ser739)抗体

产品编号 YB-10016R
英文名称 phospho-ZCWCC1 (Ser739)
中文名称 ***酸化ZCWCC1抗体
别    名 AC004542.C22.1.; p-MORC2(Ser739); phospho-ZCWCC1(Ser739); CW type with coiled coil domain 1; KIAA0852; ZCW3; ZCWCC1; Zinc finger; Zinc finger CW type coiled coil domain protein 1; Zinc finger CW type with coiled coil domain 1; Zing finger CW type 3 zinc finger CW-type coiled-coil domain protein 1; MORC family CW-type zine finger 2; MORC2.  
规格价格 100ul/1580元 购买        大包装/询价
说 明 书 100ul  
产品类型 ***酸化抗体 
研究领域 细胞生物  转录调节因子  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 114kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MORC2 around the phosphorylation site of Ser739:KR(p-S)VA 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: The CW domain is a structural module found in many vertebrate, parasitic and plant proteins. It consists of a mononuclear four-cysteine zinc-finger domain that plays a role in DNA binding, chromatin methylation and early embryonic development. ZCWCC1 (zinc finger CW-type coiled-coil domain protein 1), also known as MORC2 (MORC family CW-type zinc finger protein 2) or ZCW3, is a 1,032 amino acid protein that contains one CW-type zinc finger domain. ZCWCC1 is located on chromosome 22 and is ubiquitously expressed with highest expression in pancreas, smooth muscle and testis. Expression of ZCWCC1 is upregulated in hypoxia, a pathological condition characterized by an inadequate supply of oxygen in the blood. Function: May act as a transcriptional repressor. Down-regulates CA9 expression. Subunit: Interacts with HDAC4.  Subcellular Location: Nucleus. Cytoplasm, cytosol. Note=Mainly located in the nucleus. Tissue Specificity: Highly expressed in smooth muscle, pancreas and testis. Similarity: Contains 1 CW-type zinc finger. SWISS: Q9Y6X9 Gene ID: 22880 Database links:

Entrez Gene: 22880 Human

Entrez Gene: 74522 Mouse

Entrez Gene: 289736 Rat

SwissProt: Q9Y6X9 Human

Unigene: 143840 Human

Unigene: 555918 Human

Unigene: 139127 Mouse

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Tissue/cell: rat pancreas tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-phospho-ZCWCC1(Ser739) Polyclonal Antibody, Unconjugated(bs-10016R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining