Mouse KIM-1 ELISA Kit

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单价: 495.00
品牌: innov-research
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更新: 2019-06-11
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货号: IRKTAH1160
供应商: 上海钰博生物科技有限公司
数量: 大量
英文名: Mouse KIM-1 ELISA Kit
保质期: 1年
保存条件: -2-8℃
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Mouse KIM-1 ELISA Kit

Product Description

Mouse KIM1 ELISA Kit


Our Mouse KIM1 ELISA Kit is a sandwich ELISA intended for the quantitative determination of Mouse KIM1 in cell culture supernates, tissue homogenates, serum, plasma (heparin, EDTA) and urine.

KIM1(TIM-1), also known as Hepatitis A virus cellular receptor 1, is a protein that in Mouses is encoded by the HAVCR1 gene.123 Infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV led Feigelstock et al.(1998) to conclude that the protein is indeed a receptor for the virus. Immunofluorescence microscopy demonstrated internalization of HAV by dog cells expressing HAVCR1. Using a monoclonal antibody to mouse Tim1, Umetsu et al.(2005) showed that Tim1 was expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. By homology of synteny with the mouse Tim1 gene and database analysis, McIntire et al.(2001) mapped the HAVCR1 gene to 5q33.2. The standard used in this kit is recombinant mouse KIM-1, constituting from Y22-T212 amino acids, and 191amino acids with the molecular mass of 21.8KDa.

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温馨提示:不可用于临床治疗。