Recombinant Human IL-1 beta

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更新: 2020-09-20
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货号: HZ-1164
英文名: Recombinant Human IL-1 beta
规格: 10 µg

IL-1 beta (Recombinant Human)

Product Description:

  Human Cell Expressed
  Animal-derived product free
  Endotoxin-free*
  Very High Activity

HumanKine® IL-1 beta expressed in human 293 cells has a very high activity with a typical ED50 of 0.02 to 0.08 ng/mL using a bioassay to measure stimulation of the proliferation of mouse D10S cells. In comparison with the E. coli expressed protein, IL-1 beta® is 50% more potent promoting human CD4+ T cell differentiation into Th17 cells. This cytokine is produced in a serum-free, chemically defined media.

Technical Specifications:

  Species: Human
  Expression: Human Cell Expressed
  Activity: 0.02 to 0.08 ng/mL ED50
  Purity: >95%
  Endotoxin: Endotoxin-free*
  Molecular Mass: 18 and 25 kDa, monomer, glycosylated

Activity Assay:

The specific activity was determined by the dose-dependent stimulation of the proliferation of mouse D10S cells.

Purity Confirmation:

The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.


*Endotoxin-free: <0.5 EU/µg

All HumanKine proteins are expressed in the HumaXpress® human cell expression system and have low endotoxin levels with native human post-translational modifications and folding.

温馨提示:不可用于临床治疗。