Anti-HLADQA1 + HLADQA2抗体

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单价: 1380.00
品牌: Ybscience
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更新: 2024-03-29
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 Anti-HLADQA1 + HLADQA2抗体

产品编号 YB-18043R
英文名称 HLADQA1 + HLADQA2
中文名称 组织相容性抗原DQA1/DQA2抗体
别    名 CD; CELIAC1; DC-1 alpha; DC-1 alpha chain; DQ-A1; DX alpha chain; DX-ALPHA; FLJ27088; FLJ27328; GSE; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA class II histocompatibility antigen, DQ(W3) alpha chain; HLA-DCA; HLA-DQA; HLA-DQA2; HLA-DXA; leucocyte antigen DQA1; leukocyte antigen alpha chain; major histocompatibility complex, class II, DQ alpha 1; major histocompatibility complex, class II, DQ alpha 2; MGC149527; MHC class II antigen; MHC class II DQA1; MHC class II DQA2; MHC class II HLA-D alpha glycoprotein; MHC class II HLA-DQ-alpha-1; MHC class II surface glycoprotein; MHC HLA-DQ alpha.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Chimpanzee, Cynomolgus Monkey
产品应用 WB=1:500-2000 ELISA=1:500-1000   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HLADQA1 + HLADQA2:51-150/254 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008] Function: HLADQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). HLADQA2 forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Subcellular Location: Endoplasmic reticulum, Golgi Apparatus and Plasma membrane SWISS: P01906 Gene ID: 3117 3118 Database links:

Entrez Gene: 3117 Human

Entrez Gene: 3118 Human

Omim: 146880 Human

Omim: 613503 Human

SwissProt: P01906 Human

SwissProt: P01909 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Sample:  A431(Human) Cell Lysate at 30 ug Primary: Anti-HLADQA1 + HLADQA2 (bs-18043R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 36 kD